This link is to a 4 minute video that outlines the current state of knowledge about the causes and direction of research designed to help develop effective treatment for dementia. It presents the neurophysiological, biochemical, genetic, and lifestyle factors that influence the emergence and progression of the disease. I was left wondering as I often am in these situations, why are they leaving out the fact that the neuronal equation has an electrical component that can be directly modified without the need for drugs or other more invasive measures being required. I'm referring to the use of near infrared light stimulation (photobiomodulation) and behavioral conditioning techniques (biofeedback) or neurofeedback when modifying brainwave activity.
Our clinical work with patients led to developing a combined treatment protocol that has shown to be effective in slowing and in some circumstances there has been a reversal of cognitive and behavioral symptoms. The mechanism of actioin appears to be the improving of cortical perfusion or blood flow and the reduction of brain inflammation due to the incrased production of ATP and other biochemical changes that prevent neuronal survival, repair, and regeneration.
Clinical trials on the use of photobiomodulation are demonstrating the effectiveness of light to remediate symptoms of both Parkinson's and dementia.